Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the procedure of various myeloma. Its synthesis or analyze is important for making certain the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound within the synthesis of imatinib, a drug that targets specific types of most cancers, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their analyze is crucial for optimizing the manufacturing course of action and making certain substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to treat breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. A variety of intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in treating cancers including ovarian, breast, and lung cancer.
three. Other 17-Diol 17-Acetate Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the therapy of colorectal most cancers and small mobile lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved in the synthesis of adamantane derivatives, that have a variety of purposes, together with antiviral Houses.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to regulate blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of varied gluconic acid derivatives, that are used in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilised to N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine control style 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).